05 // What each test amount meant
Which AOD-9604 Dosage Amounts Belonged to Which Tests?
Every amount came from an old test in people or animals. None tells you what to use.
Why can't a test amount tell you what to take?
A number on a vial can look like a doctor's order. The AOD-9604 amounts below only record what scientists tested.
No human amount led to more weight loss than a placebo [12]. That means no tested amount became a proven dose for weight loss.
Each number belongs to a certain animal or human test. The way the drug entered the body and the length of the test also changed what the number meant.
One pig cleared half the drug from its blood in about 3 minutes [6]. That animal fact can't guide use at home.
Which amount was used in each kind of test?
One mouse test used a related piece of growth hormone by mouth. In a separate 14-day test, scientists put AOD-9604 into the bellies of heavy mice, including some born without the fat-cell protein needed for the lasting result and kept for comparison [1].
An early human test put the drug into a vein and set the amount by body weight. Later human tests used 0.25 mg to 54 mg by mouth each day.
One 24-week human test compared 0.25 mg, 0.5 mg, and 1 mg daily [5]. No amount became a proven dose for losing weight.
A rabbit knee test used 0.25 mg each week for 4-7 weeks. Those shots went into rabbit knees, not into a person's vein or stomach.
The 14-day test belonged to mice, while the weekly 0.25 mg test belonged to rabbit knees. These old amounts aren't steps for you to follow.
How did the drug enter the body during tests?
Scientists tried four ways: by mouth, into a vein, into a knee, and inside a mouse's belly. Human weight work mainly used pills, while the arthritis work used rabbit knee shots [5][6].
A pig cleared half the drug from its blood in about 3 minutes after a vein dose [6]. That speed says nothing about the safety of an under-skin shot in a person.
No paper gives a useful storage time or temperature after the drug is dried by freezing. That drying test cannot help you judge a vial.
The main human papers also give no clear answer on how long the drug stays usable [6]. A label can't tell you how a seller handled the vial before it arrived.
Did any tested amount improve human weight loss?
During the 2000s, roughly 900 adults joined about six tests. They swallowed 0.25 mg to 54 mg each day for periods from 7 days through 24 weeks [5].
The drug and placebo groups had much the same complaints [5]. The strongest test also found no added fall on the scale.
Metabolic Pharmaceuticals dropped its obesity project around 2007 [12]. No use or human amount gained approval.
This page can't give you a personal dose plan. It lists old amounts from AOD-9604 research and links each finding to the AOD-9604 references.